Repeated Schistosoma japonicum infection following treatment in two cohorts: evidence for host susceptibility to helminthiasis?

/ / Faculty Research in Asia, Research

CGPH AFFILIATED FACULTY: Robert Spear

DATE OF PUBLICATION: March 2013

REGION: Asia (Sichuan, China)

REFERENCE: Carlton EJ, Hubbard A, Wang S, Spear RC. Repeated Schistosoma japonicum infection following treatment in two cohorts: evidence for host susceptibility to helminthiasis? PLoS Negl Trop Dis. 2013;7(3):e2098. doi: 10.1371/journal.pntd.0002098. Epub 2013 Mar 7.

SUMMARY/ABSTRACT: In light of multinational efforts to reduce helminthiasis, we evaluated whether there exist high-risk subpopulations for helminth infection. Such individuals are not only at risk of morbidity, but may be important parasite reservoirs and appropriate targets for disease control interventions. We followed two longitudinal cohorts in Sichuan, China to determine whether there exist persistent human reservoirs for the water-borne helminth, Schistosoma japonicum, in areas where treatment is ongoing. Participants were tested for S. japonicum infection at enrollment and two follow-up points. All infections were promptly treated with praziquantel.

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