High rates of o’nyong nyong and chikungunya virus transmission in coastal kenya.

/ / Faculty Research in Africa, Research

CGPH FACULTY: Desiree LaBeau

DATE OF PUBLICATION: February 2015

REGION: Africa

REFERENCE: LaBeaud AD, Banda T, Brichard J, Muchiri EM, Mungai PL, Mutuku FM, Borland E, Gildengorin G, Pfeil S, Teng CY, Long K, Heise M, Powers AM, Kitron U, King CH. High rates of o’nyong nyong and chikungunya virus transmission in coastal kenya. PLoS Negl Trop Dis. 2015 Feb 6;9(2):e0003436. doi: 10.1371/journal.pntd.0003436. eCollection 2015 Feb.

SUMMARY/ABSTRACT: Chikungunya virus (CHIKV) and o’nyong nyong virus (ONNV) are mosquito-borne alphaviruses endemic in East Africa that cause acute febrile illness and arthritis. The objectives of this study were to measure the seroprevalence of CHIKV and ONNV in coastal Kenya and link it to demographics and other risk factors. Alphavirus exposure, particularly ONNV exposure, is common in coastal Kenya with ongoing interepidemic transmission of both ONNV and CHIKV. Women and adults were more likely to be seropositive. Household location may be a defining factor for the ecology of alphaviral transmission in this region.

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