Neurodevelopmental performance among school age children in rural Guatemala is associated with prenatal and postnatal exposure to carbon monoxide, a marker for exposure to woodsmoke.

/ / Faculty Research in Latin America, Research

CGPH FACULTY: Brenda Eskenazi, John Balmes, Kirk R. Smith

DATE OF PUBLICATION: September 2011

REGION: Latin America

REFERENCE: Dix-Cooper L, Eskenazi B, Romero C, Balmes J, Smith KR. Neurodevelopmental performance among school age children in rural Guatemala is associated with prenatal and postnatal exposure to carbon monoxide, a marker for exposure to woodsmoke. Neurotoxicology. 2012 Mar;33(2):246-54. doi: 10.1016/j.neuro.2011.09.004. Epub 2011 Sep 24.

SUMMARY/ABSTRACT: We investigated whether early life chronic exposure to woodsmoke, using personal passive 48-h carbon monoxide (CO) as an indicator, is associated with children’s neurodevelopmental and behavioral performance. CO measures were collected every 3 months from 2002 to 2005 among mother-child dyads during the Randomized Exposure Study of Pollution Indoors and Respiratory Effects (RESPIRE) stove intervention trial in San Marcos, Guatemala. This seems to be the first study on woodsmoke exposure and neurodevelopment, and the first longitudinal birth cohort study on chronic early life CO exposures, determined by high quality measures of mothers’ and infants’ personal CO exposures, and using well-established, reliable child neuropsychological tests

ACCESS: Link to Pubmed